Estradiol and/or Ibandronate Therapy Ameliorates Oxidative Status in Livers of Ovariectomized Rats
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چکیده
منابع مشابه
17beta-estradiol prevents oxidative stress and decreases blood pressure in ovariectomized rats.
In this study, we tested whether estrogen deficiency is associated with oxidative stress and decreased nitric oxide (NO) production, which could be responsible for an increased blood pressure in ovariectomized rats. Hemodynamic studies were performed on conscious, chronically instrumented rats. Chronic estrogen replacement on ovariectomized rats lowered blood pressure approximately 13 mmHg, fro...
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Estrogen replacement is an effective therapy of postmenopausal symptoms such as hot flushes, bone loss, and vaginal dryness. Undesired estrogen effects are the stimulation of uterine and mammary gland epithelial cell proliferation as well as hepatic estrogenicity. In this study, we examined the influence of different estradiol release kinetics on tissue responsivity in ovariectomized (OVX) rats...
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Estradiol decreases meal size, food intake, and body weight in female rats. To investigate whether these effects of estradiol involve a change in the sensitivity of the signaling pathway through which pancreatic glucagon released during meals contributes to meal termination (satiation), glucagon or glucagon antibodies were infused via the hepatic portal vein in ovariectomized rats that were chr...
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Flemingia macrophylla (Leguminosae), a native plant of Taiwan, is used as folk medicine. An in vitro study showed that a 75% ethanolic extract of F. macrophylla (FME) inhibited osteoclast differentiation of cultured rat bone marrow cells, and the active component, lespedezaflavanone A (LDF-A), was isolated. It was found that oral administration of FME for 13 weeks suppressed bone loss in ovarie...
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There is increasing evidence that menopause due to oxidative imbalance will lead to metabolic disorders (1). Menopause also increases food intake and body weight gain and is associated with abnormalities in lipid metabolism (2). More recent experimental studies confirm that ovariectomy cause oxidative stress and cell damage in animals (1,3,4). Steroid hormones, particularly estrogen, are natura...
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ژورنال
عنوان ژورنال: British Journal of Medicine and Medical Research
سال: 2014
ISSN: 2231-0614
DOI: 10.9734/bjmmr/2014/7949